島根大学 材料エネルギー学部 有機金属化学分野
崔研究室
Sai Laboratory
2025年
24. Shuto Okuda, Yutaka Narita, Rikuo Hayashi, Taro Udagawa, Masahiro Sai*
1-Arylallyloxysilanes as Formal Precursors to Potassium Homoenolate
Equivalents of Ketones
Org. Lett. 2025, 27, 4762–4766. (Q1, JCR 2024)
DOI: 10.1021/acs.orglett.5c01177
(ChemRxiv 2025, preprint, DOI: 10.26434/chemrxiv-2025-t0vx1)
23. Hiroki Ishikawa, Masahiro Sai*
Chiral Potassium Brønsted Base-Catalyzed Stereoselective Synthesis of 1,3-Diols
via a Tandem Allylic Isomerization/Asymmetric Aldol–Tishchenko Reaction
Adv. Synth. Catal. 2025, accepted. (Q1, JCR 2024) Open Access
DOI: 10.1002/adsc.70108
(ChemRxiv 2025, preprint, DOI: 10.26434/chemrxiv-2025-w9479)
22. Takatoki Mizuno, Taro Udagawa, Masahiro Sai*
Asymmetric Intramolecular Oxa-Michael Addition of ε- and ζ-Hydroxy-α,β-Unsaturated
Esters Enabled by Chiral Crown Ether-Coordinated Potassium Base Catalysts
ChemRxiv 2025, preprint, DOI: 10.26434/chemrxiv-2025-lmb7j
2024年
崔 允寛
「オールドルーキーの挑戦」Message from Young Principal Researcher (MyPR)
有機合成化学協会誌 2024, 82 (4), 379–381.
DOI: 10.5059/yukigoseikyokaishi.82.379
2023年
21. Shuto Okuda, Yutaka Narita, Rikuo Hayashi, Masahiro Sai*
Regio- and Diastereoselective Synthesis of Unsymmetrical 1,4-Diketone-Derived
(Z)-Monosilyl Enol Ethers via Siloxyallylpotassium Intermediates
Chem. Commun. 2023, 59, 2939–2942.
DOI: 10.1039/D2CC07097A
(ChemRxiv, 2022, preprint, DOI: 10.26434/chemrxiv-2022-8djs0)
20. Rikuo Hayashi, Yutaka Narita, Masahiro Sai*
One-Pot Synthesis of 3-Functionalized (Z)-Silyl Enol Ethers from 1-Arylallylic
Alcohols by C,O-Difunctionalization of Dipotassio α,β-Dianion Intermediates
Org. Biomol. Chem. 2023, 21, 4206–4209.
DOI: 10.1039/D3OB00199G
(ChemRxiv, 2022, preprint, DOI: 10.26434/chemrxiv-2022-b33mt)
19. Momoka Shimaoka, Masahiro Sai*
Silver-Catalyzed Tandem Cyclization for Syntheses of Azaoxa- and Diazaspirocycles
Eur. J. Org. Chem. 2023, 26, e202201404.
DOI: 10.1002/ejoc.202201404
(ChemRxiv, 2022, preprint, DOI: 10.26434/chemrxiv-2022-j2xkk)
18. Rikuo Hayashi, Kaori Ando, Taro Udagawa, Masahiro Sai*
β-Functionalized and α,β-Difunctionalized Ketones from 1-Arylallylic Alcohols
via Dipotassio α,β-Dianion Intermediates
Adv. Synth. Catal. 2023, 365, 826–833.
DOI: 10.1002/adsc.202201047
(ChemRxiv, 2022, preprint, DOI: 10.26434/chemrxiv-2022-7whfc)
• Selected as the Front Cover in Adv. Synth. Catal. (2023, issue 6)
17. Masahiro Sai,* Takatoki Mizuno
Potassium Base-Catalyzed Redox Isomerization of Propargylic Alcohols to Chalcones
Synth. Commun. 2023, 53, 198–204.
DOI: 10.1080/00397911.2022.2152695
2022年
16. Masahiro Sai*
KOtBu/DMSO Catalytic System for Isomerization of Allylic Alcohols to Ketones
Eur. J. Org. Chem. 2022, e202200052.
DOI: 10.1002/ejoc.202200052
2021年
15. Masahiro Sai*
Potassium Base-Promoted Diastereoselective Synthesis of 1,3-Diols from Allylic Alcohols
and Aldehydes through a Tandem Allylic-Isomerization/Aldol–Tishchenko Reaction
Chem. Asian J. 2021, 16, 4053–4056.
DOI: 10.1002/asia.202101093
14. Masahiro Sai*
A Tetraarylpyrrole-Based Phosphine Ligand for the Palladium-Catalyzed Amination of
Aryl Chlorides
Adv. Synth. Catal. 2021, 363, 5422–5428.
DOI: 10.1002/adsc.202100731
13. Masahiro Sai,* Hiroaki Kurouchi
Potassium Base-Catalyzed Michael Additions of Allylic Alcohols to α,β-Unsaturated Amides:
Scope and Mechanistic Insights
Adv. Synth. Catal. 2021, 363, 3585–3591.
DOI: 10.1002/adsc.202100272
2020年まで
12. Masahiro Sai*
Direct Synthesis of Indanes via Iron-Catalyzed Dehydrative Coupling/Friedel–Crafts Cyclization of
Two Different Alcohols
Eur. J. Org. Chem. 2019, 1102–1106.
11. Masahiro Sai,* Seijiro Matsubara
Copper-Catalyzed Direct and Stereoselective Synthesis of Conjugated Enynes from α-Allenols
Adv. Synth. Catal. 2019, 361, 39–43.
10. Masahiro Sai*
An Efficient Ga(OTf)3/Isopropanol Catalytic System for Direct Reduction of Benzylic Alcohols
Adv. Synth. Catal. 2018, 360, 4330–4335.
9. Masahiro Sai*
Direct Reduction of Allylic Alcohols Using Isopropanol as Reductant
Adv. Synth. Catal. 2018, 360, 3482–3487.
DOI: 10.1002/adsc.201800731
8. Masahiro Sai,* Hisashi Yamamoto*
Chiral Brønsted Acid as a True Catalyst: Asymmetric Mukaiyama Aldol and Hosomi–Sakurai Allylation
Reactions
J. Am. Chem. Soc. 2015, 137, 7091–7094.
7. Masahiro Sai,* Matsujiro Akakura, Hisashi Yamamoto*
Chemoselective Silyl Transfer in the Mukaiyama Aldol Reaction Promoted by Super Silyl Lewis Acid
Chem. Commun. 2014, 50, 15206–15208.
DOI: 10.1039/C4CC05807K
6. Masahiro Sai, Seijiro Matsubara*
Lithium(1+)-Catalyzed Nazarov-Type Cyclization of 1-Arylbuta-2,3-dien-1-ols: Synthesis of Benzofulvene
Derivatives
Synlett, 2014, 25, 2067–2071.
DOI: 10.1055/s-0034-1378333
5. Masahiro Sai, Seijiro Matsubara*
Silver-Catalyzed Intramolecular Chloroamination of Allenes: Easy Access to Functionalized 3-Pyrroline
and Pyrrole Derivatives
Org. Lett. 2011, 13, 4676–4679.
DOI: 10.1021/ol201895s
4. Masahiro Sai, Hideki Yorimitsu,* Koichiro Oshima*
Allyl-, Allenyl-, and Propargyl-Transfer Reactions through Cleavage of C–C Bonds Catalyzed by an
N-Heterocyclic Carbene/Copper Complex: Synthesis of Multisubstituted Pyrroles
Angew. Chem. Int. Ed. 2011, 50, 3294–3298.
3. Masahiro Sai, Hideki Yorimitsu,* Koichiro Oshima*
Copper-Catalyzed Allylation of Alkyl Halides with Allylic Grignard Reagents
Bull. Chem. Soc. Jpn. 2009, 82, 1194–1196.
2. Hiroki Miura, Kenji Wada,* Saburo Hosokawa, Masahiro Sai, Teruyuki Kondo, Masashi Inoue
A Heterogeneous Ru/CeO2 Catalyst Effective for Transfer-Allylation from Homoallyl Alcohols to Aldehydes
Chem. Commun. 2009, 45, 4112–4114.
DOI: 10.1039/B901830A
1. Masahiro Sai, Hidenori Someya, Hideki Yorimitsu,* Koichiro Oshima*
Copper-Catalyzed Reaction of Alkyl Halides with Cyclopentadienylmagnesium Reagent
Org. Lett. 2008, 10, 2545–2547.
DOI: 10.1021/ol800814k